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Numerous happen to be useful mainly because they bind selectively to both the CB1 or CB2 receptors, whereas THC has a similar affinity for each. Tritium-labelled cannabinoids such as CP-fifty five,940 were being instrumental in identifying the cannabinoid receptors within the early 1990s.[fifty three]
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Some early artificial cannabinoids were also utilised clinically. Nabilone, a primary era artificial THC analog, has become used being an antiemetic to overcome vomiting and nausea since 1981.
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